The Battledome- Vegeta vs Itachi

[qwertz143]

Hulk will win because according to wikia, there have been several instances in the past where Hulk has not only spent extended periods of time underwater or in oxygen-less outer space without suffocating, but he has also moved his mouth and spoken in these environments. It appears that the Hulk's body is able to adapt itself to new inhospitable environments when necessary, so if Hulk get chucked into space or underwater he will survive and adapt. Like his healing factor, it is believed that this ability is also fueled by his rage and the madder the Hulk is, the quicker the Hulk's body will adapt.
In addition to great strength, the Hulk's body possesses a high degree of resistance to injury. The Hulk's skin is impervious to conventional blades, adamantium and vibranium being amongst the very few metals that are truly capable of piercing his skin. The Hulk is able of withstanding high caliber bullets, explosives, pressure extremes, falls from orbital heights, maximized heat without blistering, maximized cold without freezing, and great impacts. The Hulk has withstood the impact of a ground zero nuclear explosion and the full force of the the Human Torch's Nova Blast, which has a maximum temperature of 1,000,000 degrees Fahrenheit, without sustaining injury . He was also able to withstand core solar temperatures, planet-splitting impacts, and a blast from Galactus, which is the strongest weapon in Marvel history. The Hulk's durability, much like his strength, is fueled by rushes of adrenaline while angry.

Vegeta
Strengths
Very strong considering his size.
Very fast.
Energy blasts.
Super Saiyan transformations
Fighting technique.
Can fly

Weaknesses
Doesnt know his limits
His anger can make his technique sloppy.
Makes rash, and sometimes foolish decisions
Physically smaller than the Hulk
His pride
Limited supply of energy

The Hulk
Strengths
Extremely strong (stronger than Vegeta)
The angrier he gets, the stronger he gets.
A height and muscular advantage
Self healing
Near enough immune to any weapons in the MARVEL universe.
Tough skin (Which becomes tougher as he gets angrier)

Weaknesses
Lack of rational thinking
His muscle mass COULD slow him down, similar to the Ascended Saiyan form.
Cant fly, can only leap from A to B
Fairly dumb
His alter ego's traits which could sometimes seep through.

Considering all of these I say Hulk will win.
Give your thoughts, maybe SSJ4 Vegeta could defeat Hulk
But from what I think, due to Hulk's tough skin he will withstand Vegeta's attacks, till Vegeta drains all of his power, and then Hulk will finish him.